{"id":30672,"date":"2023-07-02T19:28:32","date_gmt":"2023-07-02T19:28:32","guid":{"rendered":"https:\/\/danielsmarketingblc.com\/CuratedProducts\/?p=30672"},"modified":"2023-07-02T19:28:33","modified_gmt":"2023-07-02T19:28:33","slug":"multiple-drug-targets-for-the-treatment-of-influenza-identified-using-ai-program","status":"publish","type":"post","link":"https:\/\/danielsmarketingblc.com\/CuratedProducts\/2023\/07\/02\/multiple-drug-targets-for-the-treatment-of-influenza-identified-using-ai-program\/","title":{"rendered":"Multiple drug targets for the treatment of influenza identified using AI program"},"content":{"rendered":"<div id=\"body-0f0627f6-8f3c-4f17-b452-08f4639c651b\" itemprop=\"articleBody\">\n            <span itemprop=\"author\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/Organization\"><meta itemprop=\"name\" content=\"News Medical\"><meta itemprop=\"url\" content=\"https:\/\/www.news-medical.net\/\"><\/span><\/p>\n<p>Poolbeg Pharma,\u00a0a clinical-stage biopharmaceutical company specializing in infectious and other prevalent diseases with a high unmet medical need, declares a big breakthrough in its world first influenza Artificial Intelligence (&#8216;AI&#8217;) Programme with CytoReason. Poolbeg has been working with CytoReason since March 2022.<\/p>\n<p>Poolbeg\u2019s unique disease progression data from influenza human challenge trials combined with CytoReason\u2019s broad repositories of curated disease data were analyzed using CytoReason\u2019s industry-leading AI-led platform. The evaluation has led to the invention of multiple novel drug targets for the treatment of influenza.<\/p>\n<p>Identification of drug targets from this unique data-set has previously been successful as p38 MAP Kinase, inhibited by POLB 001, was identified as a driver of severe influenza but this required manual evaluation that took several years. Nonetheless, through the utilization of CytoReason\u2019s cutting-edge AI technology, Poolbeg has now identified multiple novel drug targets in only 15 months. Furthermore, CytoReason\u2019s evaluation independently confirmed the importance of the p38 MAP kinase pathway in influenza, providing further validation for Poolbeg\u2019s POLB 001 programme.<\/p>\n<p>The Company is actively exploring probably the most effective option to further develop the novel drug targets with a purpose to generate value and appears forward to updating shareholders in regards to the progress of this programme in the end. This marks Poolbeg\u2019s second successful AI Programme, following the identification of potential latest drug candidates for Respiratory Syncytial Virus (RSV) announced in December 2022.<\/p>\n<p><!-- end mobile middle mrec --><\/p>\n<blockquote>\n<p><em>Our collaboration with CytoReason has put Poolbeg on the forefront of AI drug discovery. CytoReason\u2019s deep interrogation of the uniquely wealthy data derived from human challenge trials has deepened our knowledge of influenza, leading to the identification of multiple novel influenza drug targets. There may be a big unmet need for brand spanking new and higher treatments for vulnerable patients with influenza and this can be a major milestone within the delivery of recent therapies that may improve patient outcomes and global health.\u201d<\/em><\/p>\n<p style=\"text-align: right;\"><em>\u200b\u200b\u200b\u200b\u200b\u200b\u200b<\/em>Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma<\/p>\n<\/blockquote>\n<p>David Harel, Chief Executive Officer of CytoReason, said:<strong>\u00a0<\/strong><em>&#8220;Once more, we\u2019re pleased to see that leveraging CytoReason\u2019s computational disease models to extract insight<\/em><em>s<\/em><em> from Poolbeg\u2019s unique human challenge data can optimise the goal discovery process. <\/em><em>More importantly, t<\/em><em>hese impressive results wouldn&#8217;t be possible without the commitment, transparen<\/em><em>cy<\/em><em>, and reciproc<\/em><em>ity<\/em>\u00a0<em>of each teams<\/em><em>.\u201d<\/em><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Poolbeg Pharma,\u00a0a clinical-stage biopharmaceutical company specializing in infectious and other prevalent diseases with a high unmet medical need, declares a big breakthrough in its world first influenza Artificial Intelligence (&#8216;AI&#8217;) Programme with CytoReason. Poolbeg has been working with CytoReason since March 2022. Poolbeg\u2019s unique disease progression data from influenza human challenge trials combined with CytoReason\u2019s [&#8230;]\n","protected":false},"author":1,"featured_media":30673,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"fifu_image_url":"https:\/\/d2jx2rerrg6sh3.cloudfront.net\/image-handler\/picture\/2014\/7\/Influenza-620x480.jpg","fifu_image_alt":"","two_page_speed":[],"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[97],"tags":[1822,1646,588,1821,1211,1823,464],"class_list":["post-30672","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-drug","tag-identified","tag-influenza","tag-multiple","tag-program","tag-targets","tag-treatment"],"aioseo_notices":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin 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