IU School of Medicine researchers are taking steps to enhance the accessibility and quality of look after adolescents experiencing opioid use disorder (OUD) and other substance use disorders (SUDs), because of a brand new $5 million grant from the National Institute of Health’s Helping to End Addiction Long-Term (HEAL) Initiative. The grant will fund the […]
Researchers from Tokyo Metropolitan University have identified key aspects within the mechanism behind DNA repair in our bodies. For the primary time, they showed that the “proofreading” portion of the DNA replicating enzyme polymerase epsilon ensured secure termination of replication at damaged portions of the DNA strand, ultimately saving DNA from severe damage. This recent […]
Imagine the lifetime of a yeast cell, floating across the kitchen in a spore that eventually lands on a bowl of grapes. Life is sweet: food for days, not less than until someone notices the rotting fruit and throws them out. But then the sun shines through a window, the section of the counter where […]
In a review article published within the journal Heliyon, scientists have provided an in depth overview of the dietary, pharmacological, and sensory properties of maple syrup. Background Maple syrup is a natural sweetener that’s widely used instead choice to avoid using refined sugar. Maple syrup has a significantly lower glycemic index than refined sugar and, […]
Researchers on the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter present in red blood cells and the way it interacts with drugs. Details on the findings, which were reported within the September 7 issue of Nature Structural & Molecular Biology [DOI: 10.1038/s41594-023-01085-6], may lead to the event […]
Backed by a $26 million federal grant, researchers at three Michigan universities, a number one health care system, and a state agency will proceed a long-term study of how exposure to environmental aspects while pregnant and early childhood can impact health for a lifetime. The funding from the National Institutes of Health, or NIH, is […]
With around 90% of medication failing to make it to market, the potential for improving efficiency throughout the drug development industry is obvious. Drugs designed to combat cancers suffer similar rates of failure for a lot of reasons. Now, researchers have revealed one reason why certain anti-cancer compounds could cause unexpected unintended effects. This research […]
Yale researchers have created a functional “humanized” liver in living mice that can help scientists find human-specific mechanisms for regulating levels of cholesterol and potentially for treating chronic liver diseases afflicting tens of thousands and thousands of individuals in the US. The findings are published Aug. 9 within the journal Cell. Chronic liver diseases similar […]
B cells or B lymphocytes are a crucial a part of the body’s immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, resulting in their uncontrolled proliferation. The induction of immortalized B cells is step one in the event of posttransplant […]
University of Virginia School of Medicine researchers have discovered a key driver of chronic inflammation that accelerates aging. That finding could allow us to slow the clock to live longer, healthier lives, and will allow us to forestall age-related conditions reminiscent of deadly heart disease and devastating brain disorders that rob us of our schools. […]