Tag Archives: exposure

Do stroke and hypertension mediate associations between exposure to air pollutants and dementia?

Do stroke and hypertension mediate associations between exposure to air pollutants and dementia?

In a recent study published in JAMA Network Open, researchers investigated whether stroke or hypertension modifies or mediates the connection between particulate matter exposure (PM2.5) within the air and new-onset dementia in america. Study: Hypertension and Stroke as Mediators of Air Pollution Exposure and Incident Dementia. Image Credit: pikselstock/Shutterstock.com Background The cognitive decline amongst individuals with dementia […]

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Early viral exposure in mice weakens vaccine response, raising questions for human studies

In a preprint* research paper recently uploaded to the bioRxiv server, researchers at Washington University investigated how the exposome can mediate immune function in house mice, probably the most widely used model systems for in vivo immunological experimentation. Mice were sequentially inoculated with six different viral pathogens from formative years (neonatal) stages, following which their […]

Cadmium exposure disrupts placental hormones, harming fetal development

Cadmium exposure disrupts placental hormones, harming fetal development

As with many toxins, exposure to the toxic metal cadmium while pregnant can adversely impact fetal development. Now, researchers on the Rutgers School of Public Health think they’re starting to know how the metal inflicts its damage: by disrupting placental hormones that regulate pregnancy physiology. Unlike other toxins, relatively little cadmium crosses the placenta to […]

Long-term high fluoride exposure during adolescence causes hippocampal impairments

Long-term high fluoride exposure during adolescence causes hippocampal impairments

In a recent study published in Scientific Reports, researchers evaluated the impacts of prolonged fluoride exposure during adolescence and maturity on cognition and associated hippocampal alterations. Study: Prolonged exposure to high fluoride levels during adolescence to maturity elicits molecular, morphological, and functional impairments within the hippocampus. Image Credit: SedovaY / Shutterstock.com Background Fluoride, a naturally occurring chemical […]