Stem cells can differentiate to interchange dead and damaged cells. But how do stem cells resolve which form of cell to turn out to be in a given situation? Using intestinal organoids, the group of Bon-Kyoung Koo at IMBA and the Institute for Basic Science identified a brand new gene, Daam1, that plays a vital […]
A research team from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has now demonstrated for the primary time the central role of macrophages within the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration. Particularly, it could possibly be described that macrophages produce […]
Researchers on the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter present in red blood cells and the way it interacts with drugs. Details on the findings, which were reported within the September 7 issue of Nature Structural & Molecular Biology [DOI: 10.1038/s41594-023-01085-6], may lead to the event […]
In accordance with recent research within the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to assist them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is thought to manage gene expression programs within the nucleus, but it surely also now appears to operate […]
B cells or B lymphocytes are a crucial a part of the body’s immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, resulting in their uncontrolled proliferation. The induction of immortalized B cells is step one in the event of posttransplant […]
University of Texas at Dallas scientists have discovered a previously unknown “housekeeping” process in kidney cells that ejects unwanted content, leading to cells that rejuvenate themselves and remain functioning and healthy. The self-renewal process, which is fundamentally different from how other bodily tissues are thought to regenerate, helps explain how, barring injury or disease, the […]